Divergent evolution of life span associated with mitochondrial DNA evolution
Само за регистроване кориснике
2017
Аутори
Stojković, BiljanaSayadi, Ahmed
Đorđević, Mirko
Jović, Jelena
Savković, Uroš
Arnqvist, Goran
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Mitochondria play a key role in ageing. The pursuit of genes that regulate variation in life span and ageing have shown that several nuclear-encoded mitochondrial genes are important. However, the role of mitochondrial encoded genes (mtDNA) is more controversial and our appreciation of the role of mtDNA for the evolution of life span is limited. We use replicated lines of seed beetles that have been artificially selected for long or short life for gt 190 generations, now showing dramatic phenotypic differences, to test for a possible role of mtDNA in the divergent evolution of ageing and life span. We show that these divergent selection regimes led to the evolution of significantly different mtDNA haplotype frequencies. Selection for a long life and late reproduction generated positive selection for one specific haplotype, which was fixed in most such lines. In contrast, selection for reproduction early in life led to both positive selection as well as negative frequency-dependent sel...ection on two different haplotypes, which were both present in all such lines. Our findings suggest that the evolution of life span was in part mediated by mtDNA, providing support for the emerging general tenet that adaptive evolution of life-history syndromes may involve mtDNA.
Кључне речи:
Acanthoscelides obtectus / artificial selection / Bruchinae / coadaptation / mitochondria / mtDNA / negative frequency dependent selection / senescenceИзвор:
Evolution, 2017, 71, 1, 160-166Издавач:
- Wiley, Hoboken
Финансирање / пројекти:
- European Research Council - GENCON AdG-294333
- Swedish Research Council - 621-2010-5266
- Еволуција у лабораторији и адаптације у природи (RS-MESTD-Basic Research (BR or ON)-173007)
DOI: 10.1111/evo.13102
ISSN: 0014-3820
PubMed: 27778315
WoS: 000394439600014
Scopus: 2-s2.0-85001861223
Институција/група
IZBISTY - JOUR AU - Stojković, Biljana AU - Sayadi, Ahmed AU - Đorđević, Mirko AU - Jović, Jelena AU - Savković, Uroš AU - Arnqvist, Goran PY - 2017 UR - https://plantarum.izbis.bg.ac.rs/handle/123456789/471 AB - Mitochondria play a key role in ageing. The pursuit of genes that regulate variation in life span and ageing have shown that several nuclear-encoded mitochondrial genes are important. However, the role of mitochondrial encoded genes (mtDNA) is more controversial and our appreciation of the role of mtDNA for the evolution of life span is limited. We use replicated lines of seed beetles that have been artificially selected for long or short life for gt 190 generations, now showing dramatic phenotypic differences, to test for a possible role of mtDNA in the divergent evolution of ageing and life span. We show that these divergent selection regimes led to the evolution of significantly different mtDNA haplotype frequencies. Selection for a long life and late reproduction generated positive selection for one specific haplotype, which was fixed in most such lines. In contrast, selection for reproduction early in life led to both positive selection as well as negative frequency-dependent selection on two different haplotypes, which were both present in all such lines. Our findings suggest that the evolution of life span was in part mediated by mtDNA, providing support for the emerging general tenet that adaptive evolution of life-history syndromes may involve mtDNA. PB - Wiley, Hoboken T2 - Evolution T1 - Divergent evolution of life span associated with mitochondrial DNA evolution EP - 166 IS - 1 SP - 160 VL - 71 DO - 10.1111/evo.13102 ER -
@article{ author = "Stojković, Biljana and Sayadi, Ahmed and Đorđević, Mirko and Jović, Jelena and Savković, Uroš and Arnqvist, Goran", year = "2017", abstract = "Mitochondria play a key role in ageing. The pursuit of genes that regulate variation in life span and ageing have shown that several nuclear-encoded mitochondrial genes are important. However, the role of mitochondrial encoded genes (mtDNA) is more controversial and our appreciation of the role of mtDNA for the evolution of life span is limited. We use replicated lines of seed beetles that have been artificially selected for long or short life for gt 190 generations, now showing dramatic phenotypic differences, to test for a possible role of mtDNA in the divergent evolution of ageing and life span. We show that these divergent selection regimes led to the evolution of significantly different mtDNA haplotype frequencies. Selection for a long life and late reproduction generated positive selection for one specific haplotype, which was fixed in most such lines. In contrast, selection for reproduction early in life led to both positive selection as well as negative frequency-dependent selection on two different haplotypes, which were both present in all such lines. Our findings suggest that the evolution of life span was in part mediated by mtDNA, providing support for the emerging general tenet that adaptive evolution of life-history syndromes may involve mtDNA.", publisher = "Wiley, Hoboken", journal = "Evolution", title = "Divergent evolution of life span associated with mitochondrial DNA evolution", pages = "166-160", number = "1", volume = "71", doi = "10.1111/evo.13102" }
Stojković, B., Sayadi, A., Đorđević, M., Jović, J., Savković, U.,& Arnqvist, G.. (2017). Divergent evolution of life span associated with mitochondrial DNA evolution. in Evolution Wiley, Hoboken., 71(1), 160-166. https://doi.org/10.1111/evo.13102
Stojković B, Sayadi A, Đorđević M, Jović J, Savković U, Arnqvist G. Divergent evolution of life span associated with mitochondrial DNA evolution. in Evolution. 2017;71(1):160-166. doi:10.1111/evo.13102 .
Stojković, Biljana, Sayadi, Ahmed, Đorđević, Mirko, Jović, Jelena, Savković, Uroš, Arnqvist, Goran, "Divergent evolution of life span associated with mitochondrial DNA evolution" in Evolution, 71, no. 1 (2017):160-166, https://doi.org/10.1111/evo.13102 . .