Jelikic-Stankov, M.

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Determination of Pefloxacin in Serum and Pharmaceutical Forms by Derivative Spectrophotometry

Đurđević, P.; Jelikic-Stankov, M.; Milićević, Zoran

(Springer Verlag, 1997)

TY  - JOUR
AU  - Đurđević, P.
AU  - Jelikic-Stankov, M.
AU  - Milićević, Zoran
PY  - 1997
UR  - https://plantarum.izbis.bg.ac.rs/handle/123456789/6
AB  - A method for the direct determination of pefloxacin in serum and pharmaceutical forms (tablets and ampoules) has been developed, based on the use of second-order derivative ultraviolet spectra. Spectrophotometric assay of pefloxacin in tablets and ampoules was carried out in 0.1 mol/L NaOH, while in serum it was performed in 0.1 mol/L NaOH with the addition of sodium dodecylsulfate, in 337-347 nm wavelength range. Linear calibration curves were obtained in the concentration ranges 2-30μg/mL pefloxacin for tablets and ampoules and 0.12-5μg/ mL for serum samples. Relative error of determination, as criterion for accuracy, was less than 1%, while the precision was better than 4ng/ml. The minimum detectable concentration of pefloxacin in serum was 15ng/mL.
PB  - Springer Verlag
T2  - Mikrochimica Acta
T1  - Determination of Pefloxacin in Serum and Pharmaceutical Forms by Derivative Spectrophotometry
EP  - 206
IS  - 3
SP  - 203
VL  - 126
DO  - 10.1007/BF01242321
ER  - 
@article{
author = "Đurđević, P. and Jelikic-Stankov, M. and Milićević, Zoran",
year = "1997",
abstract = "A method for the direct determination of pefloxacin in serum and pharmaceutical forms (tablets and ampoules) has been developed, based on the use of second-order derivative ultraviolet spectra. Spectrophotometric assay of pefloxacin in tablets and ampoules was carried out in 0.1 mol/L NaOH, while in serum it was performed in 0.1 mol/L NaOH with the addition of sodium dodecylsulfate, in 337-347 nm wavelength range. Linear calibration curves were obtained in the concentration ranges 2-30μg/mL pefloxacin for tablets and ampoules and 0.12-5μg/ mL for serum samples. Relative error of determination, as criterion for accuracy, was less than 1%, while the precision was better than 4ng/ml. The minimum detectable concentration of pefloxacin in serum was 15ng/mL.",
publisher = "Springer Verlag",
journal = "Mikrochimica Acta",
title = "Determination of Pefloxacin in Serum and Pharmaceutical Forms by Derivative Spectrophotometry",
pages = "206-203",
number = "3",
volume = "126",
doi = "10.1007/BF01242321"
}
Đurđević, P., Jelikic-Stankov, M.,& Milićević, Z.. (1997). Determination of Pefloxacin in Serum and Pharmaceutical Forms by Derivative Spectrophotometry. in Mikrochimica Acta
Springer Verlag., 126(3), 203-206.
https://doi.org/10.1007/BF01242321
Đurđević P, Jelikic-Stankov M, Milićević Z. Determination of Pefloxacin in Serum and Pharmaceutical Forms by Derivative Spectrophotometry. in Mikrochimica Acta. 1997;126(3):203-206.
doi:10.1007/BF01242321 .
Đurđević, P., Jelikic-Stankov, M., Milićević, Zoran, "Determination of Pefloxacin in Serum and Pharmaceutical Forms by Derivative Spectrophotometry" in Mikrochimica Acta, 126, no. 3 (1997):203-206,
https://doi.org/10.1007/BF01242321 . .
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