TY  - JOUR
AU  - Stikić, Radmila
AU  - Milincić, Danijel
AU  - Kostić, Aleksandar
AU  - Jovanović, Zorica
AU  - Gašić, Uroš
AU  - Tešić, Živoslav
AU  - Djordjević, Nataša
AU  - Savić, Sladjana
AU  - Czekus, Borisz
AU  - Pešić, Mirjana
PY  - 2020
UR  - https://plantarum.izbis.bg.ac.rs/handle/123456789/853
AB  - BACKGROUND: and objectives Quinoa is considered to be a "natural functional food" due to a lot of bioactive compounds that are beneficial for human health by helping prevent the risks of different diseases. The aim of this study was to test the health-promoting characteristics of Puno and Titicaca quinoa seeds grown in Serbia by assessing their phenolic and flavonoid content, antioxidant activities, and potential anticancer effect on human colorectal cancer cells. Findings Thirteen phenolic compounds were identified and quantified in the seeds of both cultivars, but their profile and concentration of individual phenolic compounds differed. Cytotoxic activities were present in both cultivars, whereas the pronounced concentration and time-dependent effects were more expressed in Puno extracts. Conclusions The extracts of the seeds of both cultivars are a rich source of phenolic and flavonoid compounds and with high antioxidant activities. Potent anticancer activity against the human colorectal cancer was expressed in both investigated cultivars. Significance and novelty The study confirmed the health benefit potential of Puno and Titicaca quinoa cultivars, grown in Serbia. These results are the first to demonstrate a potent anticancer activity of quinoa seed extract against the human colorectal cancer cell line HCT-116, as well as the presence of 7 new phenolic and flavonoid compounds.
PB  - Wiley
T2  - Cereal Chemistry
T1  - Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars
EP  - 633
IS  - 3
SP  - 626
VL  - 97
DO  - 10.1002/cche.10278
ER  - 

@article{
author = "Stikić, Radmila and Milincić, Danijel and Kostić, Aleksandar and Jovanović, Zorica and Gašić, Uroš and Tešić, Živoslav and Djordjević, Nataša and Savić, Sladjana and Czekus, Borisz and Pešić, Mirjana",
year = "2020",
abstract = "BACKGROUND: and objectives Quinoa is considered to be a "natural functional food" due to a lot of bioactive compounds that are beneficial for human health by helping prevent the risks of different diseases. The aim of this study was to test the health-promoting characteristics of Puno and Titicaca quinoa seeds grown in Serbia by assessing their phenolic and flavonoid content, antioxidant activities, and potential anticancer effect on human colorectal cancer cells. Findings Thirteen phenolic compounds were identified and quantified in the seeds of both cultivars, but their profile and concentration of individual phenolic compounds differed. Cytotoxic activities were present in both cultivars, whereas the pronounced concentration and time-dependent effects were more expressed in Puno extracts. Conclusions The extracts of the seeds of both cultivars are a rich source of phenolic and flavonoid compounds and with high antioxidant activities. Potent anticancer activity against the human colorectal cancer was expressed in both investigated cultivars. Significance and novelty The study confirmed the health benefit potential of Puno and Titicaca quinoa cultivars, grown in Serbia. These results are the first to demonstrate a potent anticancer activity of quinoa seed extract against the human colorectal cancer cell line HCT-116, as well as the presence of 7 new phenolic and flavonoid compounds.",
publisher = "Wiley",
journal = "Cereal Chemistry",
title = "Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars",
pages = "633-626",
number = "3",
volume = "97",
doi = "10.1002/cche.10278"
}

Stikić, R., Milincić, D., Kostić, A., Jovanović, Z., Gašić, U., Tešić, Ž., Djordjević, N., Savić, S., Czekus, B.,& Pešić, M.. (2020). Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars. in Cereal Chemistry
Wiley., 97(3), 626-633.
https://doi.org/10.1002/cche.10278

Stikić R, Milincić D, Kostić A, Jovanović Z, Gašić U, Tešić Ž, Djordjević N, Savić S, Czekus B, Pešić M. Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars. in Cereal Chemistry. 2020;97(3):626-633.
doi:10.1002/cche.10278 .

Stikić, Radmila, Milincić, Danijel, Kostić, Aleksandar, Jovanović, Zorica, Gašić, Uroš, Tešić, Živoslav, Djordjević, Nataša, Savić, Sladjana, Czekus, Borisz, Pešić, Mirjana, "Polyphenolic profiles, antioxidant, and in vitro anticancer activities of the seeds of Puno and Titicaca quinoa cultivars" in Cereal Chemistry, 97, no. 3 (2020):626-633,
https://doi.org/10.1002/cche.10278 . .

TY  - JOUR
AU  - Ristivojević, Petar
AU  - Stević, Tatjana
AU  - Starović, Mira
AU  - Pavlović, Slađan
AU  - Özcan, M.M.
AU  - Berić, Tanja
AU  - Dimkić, Ivica
PY  - 2020
UR  - https://plantarum.izbis.bg.ac.rs/handle/123456789/689
AB  - Aims: A multidisciplinary approach was used to compare phenolic composition, radical scavenging and antimicrobial activity of propolis samples from different geographical localities, and plant resin against various microorganisms. Methods and Results: Using UHPLC-qqqMS quantitative analysis, 28 phenolic compounds were determined. Caffeic and p-coumaric acids were identified as main phenolic acids in poplar propolis samples, except samples from Russia (P6) and China (P7). Radical scavenging activity (applying DPPH spectrophotometric assay) showed the highest activity of Serbian (40·51%) and Chinese (53·21%) propolis samples. Broth microdilution method was used for the oral cavity, fungal phytopathogenic and human vaginal isolates which have been identified at a molecular level. The most sensitive bacterial isolates were Lactobacillus acidophilus (MIC of 0·03–0·13 mg ml−1) and the oral streptococci isolates (MIC values of 0·19–0·13 mg ml−1). The most sensitive fungal phytopathogenic isolate was Fusarium oxysporum (MIC 0·003 mg ml−1). All samples, except propolis from Serbia (P4) and Turkey (P5), showed a strong antifungal activity against Fusarium sporotrichioides, Fusarium subglutinans and Fusarium proliferatum. Conclusion: The results of various tests indicate good radical scavenging and antimicrobial activity against important human and plant pathogens. Significance and Impact of the Study: A detailed propolis analysis is important when proposing a preparation of new biological antimicrobial products which have a positive impact on human health and reduce antibacterial resistance.
PB  - Wiley
T2  - Journal of Applied Microbiology
T1  - Phenolic composition and biological activities of geographically different type of propolis and black cottonwood resins against oral streptococci, vaginal microbiota and phytopathogenic Fusarium species
EP  - 310
IS  - 2
SP  - 296
VL  - 129
DO  - 10.1111/jam.14633
ER  - 

@article{
author = "Ristivojević, Petar and Stević, Tatjana and Starović, Mira and Pavlović, Slađan and Özcan, M.M. and Berić, Tanja and Dimkić, Ivica",
year = "2020",
abstract = "Aims: A multidisciplinary approach was used to compare phenolic composition, radical scavenging and antimicrobial activity of propolis samples from different geographical localities, and plant resin against various microorganisms. Methods and Results: Using UHPLC-qqqMS quantitative analysis, 28 phenolic compounds were determined. Caffeic and p-coumaric acids were identified as main phenolic acids in poplar propolis samples, except samples from Russia (P6) and China (P7). Radical scavenging activity (applying DPPH spectrophotometric assay) showed the highest activity of Serbian (40·51%) and Chinese (53·21%) propolis samples. Broth microdilution method was used for the oral cavity, fungal phytopathogenic and human vaginal isolates which have been identified at a molecular level. The most sensitive bacterial isolates were Lactobacillus acidophilus (MIC of 0·03–0·13 mg ml−1) and the oral streptococci isolates (MIC values of 0·19–0·13 mg ml−1). The most sensitive fungal phytopathogenic isolate was Fusarium oxysporum (MIC 0·003 mg ml−1). All samples, except propolis from Serbia (P4) and Turkey (P5), showed a strong antifungal activity against Fusarium sporotrichioides, Fusarium subglutinans and Fusarium proliferatum. Conclusion: The results of various tests indicate good radical scavenging and antimicrobial activity against important human and plant pathogens. Significance and Impact of the Study: A detailed propolis analysis is important when proposing a preparation of new biological antimicrobial products which have a positive impact on human health and reduce antibacterial resistance.",
publisher = "Wiley",
journal = "Journal of Applied Microbiology",
title = "Phenolic composition and biological activities of geographically different type of propolis and black cottonwood resins against oral streptococci, vaginal microbiota and phytopathogenic Fusarium species",
pages = "310-296",
number = "2",
volume = "129",
doi = "10.1111/jam.14633"
}

Ristivojević, P., Stević, T., Starović, M., Pavlović, S., Özcan, M.M., Berić, T.,& Dimkić, I.. (2020). Phenolic composition and biological activities of geographically different type of propolis and black cottonwood resins against oral streptococci, vaginal microbiota and phytopathogenic Fusarium species. in Journal of Applied Microbiology
Wiley., 129(2), 296-310.
https://doi.org/10.1111/jam.14633

Ristivojević P, Stević T, Starović M, Pavlović S, Özcan M, Berić T, Dimkić I. Phenolic composition and biological activities of geographically different type of propolis and black cottonwood resins against oral streptococci, vaginal microbiota and phytopathogenic Fusarium species. in Journal of Applied Microbiology. 2020;129(2):296-310.
doi:10.1111/jam.14633 .

Ristivojević, Petar, Stević, Tatjana, Starović, Mira, Pavlović, Slađan, Özcan, M.M., Berić, Tanja, Dimkić, Ivica, "Phenolic composition and biological activities of geographically different type of propolis and black cottonwood resins against oral streptococci, vaginal microbiota and phytopathogenic Fusarium species" in Journal of Applied Microbiology, 129, no. 2 (2020):296-310,
https://doi.org/10.1111/jam.14633 . .

TY  - JOUR
AU  - Dramicanin, Aleksandra M.
AU  - Andrić, Filip Lj.
AU  - Poštić, Dobrivoj
AU  - Momirović, Nebojša
AU  - Milojković-Opsenica, Dušanka
PY  - 2018
UR  - https://plantarum.izbis.bg.ac.rs/handle/123456789/511
AB  - This research proposes a new way of tracing differences between potato cultivation systems, botanical origin, and climate conditions by using sugar profiles. A set of 90 potato tubers of four varieties with different ripening times, cultivated in three types of agricultural systems: conventional (C), integral (I), and organic (0) were characterized based on sugar profiles of their bulk and peel. A total of nineteen sugars were quantified. In order to determine the source of variation among the types of production, the years of production and varieties, multivariate analysis of variance (MANOVA) was conducted. The results indicated that starch may be considered an important indicator of the type of production, botanical origin, and ripening time. Additionally, the analyses showed that sugar macro and microcomponents such as fructose, glucose, saccharose, sorbitol, trehalose, arabinose, turanose and maltose were the main factors for the differentiation of production types, production years and botanical origin of potato.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Journal of Food Composition and Analysis
T1  - Sugar profiles as a promising tool in tracing differences between potato cultivation systems, botanical origin and climate conditions
EP  - 65
SP  - 57
VL  - 72
DO  - 10.1016/j.jfca.2018.06.005
ER  - 

@article{
author = "Dramicanin, Aleksandra M. and Andrić, Filip Lj. and Poštić, Dobrivoj and Momirović, Nebojša and Milojković-Opsenica, Dušanka",
year = "2018",
abstract = "This research proposes a new way of tracing differences between potato cultivation systems, botanical origin, and climate conditions by using sugar profiles. A set of 90 potato tubers of four varieties with different ripening times, cultivated in three types of agricultural systems: conventional (C), integral (I), and organic (0) were characterized based on sugar profiles of their bulk and peel. A total of nineteen sugars were quantified. In order to determine the source of variation among the types of production, the years of production and varieties, multivariate analysis of variance (MANOVA) was conducted. The results indicated that starch may be considered an important indicator of the type of production, botanical origin, and ripening time. Additionally, the analyses showed that sugar macro and microcomponents such as fructose, glucose, saccharose, sorbitol, trehalose, arabinose, turanose and maltose were the main factors for the differentiation of production types, production years and botanical origin of potato.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Journal of Food Composition and Analysis",
title = "Sugar profiles as a promising tool in tracing differences between potato cultivation systems, botanical origin and climate conditions",
pages = "65-57",
volume = "72",
doi = "10.1016/j.jfca.2018.06.005"
}

Dramicanin, A. M., Andrić, F. Lj., Poštić, D., Momirović, N.,& Milojković-Opsenica, D.. (2018). Sugar profiles as a promising tool in tracing differences between potato cultivation systems, botanical origin and climate conditions. in Journal of Food Composition and Analysis
Academic Press Inc Elsevier Science, San Diego., 72, 57-65.
https://doi.org/10.1016/j.jfca.2018.06.005

Dramicanin AM, Andrić FL, Poštić D, Momirović N, Milojković-Opsenica D. Sugar profiles as a promising tool in tracing differences between potato cultivation systems, botanical origin and climate conditions. in Journal of Food Composition and Analysis. 2018;72:57-65.
doi:10.1016/j.jfca.2018.06.005 .

Dramicanin, Aleksandra M., Andrić, Filip Lj., Poštić, Dobrivoj, Momirović, Nebojša, Milojković-Opsenica, Dušanka, "Sugar profiles as a promising tool in tracing differences between potato cultivation systems, botanical origin and climate conditions" in Journal of Food Composition and Analysis, 72 (2018):57-65,
https://doi.org/10.1016/j.jfca.2018.06.005 . .

TY  - JOUR
AU  - Sedlarević, Ana
AU  - Morina, Filis
AU  - Toševski, Ivo
AU  - Gašić, Uroš
AU  - Natić, Maja
AU  - Jović, Jelena
AU  - Krstić, Oliver
AU  - Veljović-Jovanović, Sonja
PY  - 2016
UR  - https://plantarum.izbis.bg.ac.rs/handle/123456789/443
AB  - Rhinusa pilosa (Gyllenhal) is a highly specific weevil that induces stem galls on the common toadflax Linaria vulgaris Mill. females oviposit the eggs near the apex of a growing shoot. The act of oviposition is accompanied by secretion of an ovipositional fluid, which is considered to be cecidogen, directly involved in gall induction. The remains of cecidogenic fluid were collected from the surface of the oviposition point on the stem. We performed a comparative analysis of the phenolics extracted from cecidogen, the stem and galls of L. vulgaris and adult and larva of R. pilosa by HPLC-DAD. One compound with A (max) at 273, 332 nm (R (t) 30.65 min) was exclusively found in the methanol extract of cecidogen. To further characterize the cecidogen and stem phenolic profiles, we used UHPLC coupled with an OrbiTrap mass analyzer. Among 49 phenolic compounds extracted from both the ovipositional fluid and the plant, protocatechuic acid and two phenolic glycosides were exclusively found in cecidogen: diosmetin-O-acetylrutinoside and an unidentified compound. The unknown compound produced an MS2 base peak at 387 and 327 and 267 m/z base peaks at MS3 and MS4 fragmentation, respectively, and had the molecular formula C32H31O18. The plausible role of phenolic compounds in the induction of gall formation on L. vulgaris is discussed.
PB  - Springer, Dordrecht
T2  - Arthropod-Plant Interactions
T1  - Comparative analysis of phenolic profiles of ovipositional fluid of Rhinusa pilosa (Mecinini, Curculionidae) and its host plant Linaria vulgaris (Plantaginaceae)
EP  - 322
IS  - 4
SP  - 311
VL  - 10
DO  - 10.1007/s11829-016-9435-y
ER  - 

@article{
author = "Sedlarević, Ana and Morina, Filis and Toševski, Ivo and Gašić, Uroš and Natić, Maja and Jović, Jelena and Krstić, Oliver and Veljović-Jovanović, Sonja",
year = "2016",
abstract = "Rhinusa pilosa (Gyllenhal) is a highly specific weevil that induces stem galls on the common toadflax Linaria vulgaris Mill. females oviposit the eggs near the apex of a growing shoot. The act of oviposition is accompanied by secretion of an ovipositional fluid, which is considered to be cecidogen, directly involved in gall induction. The remains of cecidogenic fluid were collected from the surface of the oviposition point on the stem. We performed a comparative analysis of the phenolics extracted from cecidogen, the stem and galls of L. vulgaris and adult and larva of R. pilosa by HPLC-DAD. One compound with A (max) at 273, 332 nm (R (t) 30.65 min) was exclusively found in the methanol extract of cecidogen. To further characterize the cecidogen and stem phenolic profiles, we used UHPLC coupled with an OrbiTrap mass analyzer. Among 49 phenolic compounds extracted from both the ovipositional fluid and the plant, protocatechuic acid and two phenolic glycosides were exclusively found in cecidogen: diosmetin-O-acetylrutinoside and an unidentified compound. The unknown compound produced an MS2 base peak at 387 and 327 and 267 m/z base peaks at MS3 and MS4 fragmentation, respectively, and had the molecular formula C32H31O18. The plausible role of phenolic compounds in the induction of gall formation on L. vulgaris is discussed.",
publisher = "Springer, Dordrecht",
journal = "Arthropod-Plant Interactions",
title = "Comparative analysis of phenolic profiles of ovipositional fluid of Rhinusa pilosa (Mecinini, Curculionidae) and its host plant Linaria vulgaris (Plantaginaceae)",
pages = "322-311",
number = "4",
volume = "10",
doi = "10.1007/s11829-016-9435-y"
}

Sedlarević, A., Morina, F., Toševski, I., Gašić, U., Natić, M., Jović, J., Krstić, O.,& Veljović-Jovanović, S.. (2016). Comparative analysis of phenolic profiles of ovipositional fluid of Rhinusa pilosa (Mecinini, Curculionidae) and its host plant Linaria vulgaris (Plantaginaceae). in Arthropod-Plant Interactions
Springer, Dordrecht., 10(4), 311-322.
https://doi.org/10.1007/s11829-016-9435-y

Sedlarević A, Morina F, Toševski I, Gašić U, Natić M, Jović J, Krstić O, Veljović-Jovanović S. Comparative analysis of phenolic profiles of ovipositional fluid of Rhinusa pilosa (Mecinini, Curculionidae) and its host plant Linaria vulgaris (Plantaginaceae). in Arthropod-Plant Interactions. 2016;10(4):311-322.
doi:10.1007/s11829-016-9435-y .

Sedlarević, Ana, Morina, Filis, Toševski, Ivo, Gašić, Uroš, Natić, Maja, Jović, Jelena, Krstić, Oliver, Veljović-Jovanović, Sonja, "Comparative analysis of phenolic profiles of ovipositional fluid of Rhinusa pilosa (Mecinini, Curculionidae) and its host plant Linaria vulgaris (Plantaginaceae)" in Arthropod-Plant Interactions, 10, no. 4 (2016):311-322,
https://doi.org/10.1007/s11829-016-9435-y . .

TY  - JOUR
AU  - Waisi, Hadi
AU  - Kosović, Aleksandra
AU  - Krstić, Durda
AU  - Milojković-Opsenica, Dušanka
AU  - Nikolić, Bogdan
AU  - Dragičević, Vesna
AU  - Trifković, Jelena
PY  - 2015
UR  - https://plantarum.izbis.bg.ac.rs/handle/123456789/385
AB  - High-performance thin-layer chromatography (HPTLC) combined with image analysis and pattern recognition methods were used for fingerprinting of phenolic compounds present in seedlings of two maize genotypes ZP 434 (new generation hybrid, drought tolerant) and ZP 704 (older generation hybrid, drought sensitive) treated with different concentrations of 24-epibrassinolide. This is the first report of TLC chromatographic profile of phenolics' mixtures in maize seed extracts influenced by brassinosteroid phytohormones. Nine samples of shoot of seedlings for the whole concentration range of phytohormones (5.2 x 10(-7) -5.2 x 10(-15) M), one sample of root of seedlings treated with 5.2 x 10(-15) M 24-epibrassinolide, and the control samples of nontreated seedlings, for both genotypes, were analyzed. Phenolic profiles of root extracts indicate the absence of more polar compounds such as phenolic acids and glycosides present in shoot of seedlings. Also, hormones applied in higher concentrations have an inhibiting effect on the content of phenolics in ZP 434. Application of chemometric methods enables characterization of particular genotype of maize according to its phenolic profile.
PB  - Hindawi Limited
T2  - Journal of Chemistry
T1  - Polyphenolic Profile of Maize Seedlings Treated with 24-Epibrassinolide
DO  - 10.1155/2015/976971
ER  - 

@article{
author = "Waisi, Hadi and Kosović, Aleksandra and Krstić, Durda and Milojković-Opsenica, Dušanka and Nikolić, Bogdan and Dragičević, Vesna and Trifković, Jelena",
year = "2015",
abstract = "High-performance thin-layer chromatography (HPTLC) combined with image analysis and pattern recognition methods were used for fingerprinting of phenolic compounds present in seedlings of two maize genotypes ZP 434 (new generation hybrid, drought tolerant) and ZP 704 (older generation hybrid, drought sensitive) treated with different concentrations of 24-epibrassinolide. This is the first report of TLC chromatographic profile of phenolics' mixtures in maize seed extracts influenced by brassinosteroid phytohormones. Nine samples of shoot of seedlings for the whole concentration range of phytohormones (5.2 x 10(-7) -5.2 x 10(-15) M), one sample of root of seedlings treated with 5.2 x 10(-15) M 24-epibrassinolide, and the control samples of nontreated seedlings, for both genotypes, were analyzed. Phenolic profiles of root extracts indicate the absence of more polar compounds such as phenolic acids and glycosides present in shoot of seedlings. Also, hormones applied in higher concentrations have an inhibiting effect on the content of phenolics in ZP 434. Application of chemometric methods enables characterization of particular genotype of maize according to its phenolic profile.",
publisher = "Hindawi Limited",
journal = "Journal of Chemistry",
title = "Polyphenolic Profile of Maize Seedlings Treated with 24-Epibrassinolide",
doi = "10.1155/2015/976971"
}

Waisi, H., Kosović, A., Krstić, D., Milojković-Opsenica, D., Nikolić, B., Dragičević, V.,& Trifković, J.. (2015). Polyphenolic Profile of Maize Seedlings Treated with 24-Epibrassinolide. in Journal of Chemistry
Hindawi Limited..
https://doi.org/10.1155/2015/976971

Waisi H, Kosović A, Krstić D, Milojković-Opsenica D, Nikolić B, Dragičević V, Trifković J. Polyphenolic Profile of Maize Seedlings Treated with 24-Epibrassinolide. in Journal of Chemistry. 2015;.
doi:10.1155/2015/976971 .

Waisi, Hadi, Kosović, Aleksandra, Krstić, Durda, Milojković-Opsenica, Dušanka, Nikolić, Bogdan, Dragičević, Vesna, Trifković, Jelena, "Polyphenolic Profile of Maize Seedlings Treated with 24-Epibrassinolide" in Journal of Chemistry (2015),
https://doi.org/10.1155/2015/976971 . .