Приказ основних података о документу

dc.creatorMilisavljević, M.
dc.creatorŽivković, Svetlana
dc.creatorPekmezović, M.
dc.creatorStanković, N.
dc.creatorVojnović, S.
dc.creatorVasiljević, B.
dc.creatorSenerović, L.
dc.date.accessioned2019-04-04T16:01:57Z
dc.date.available2019-04-04T16:01:57Z
dc.date.issued2015
dc.identifier.issn1364-5072
dc.identifier.urihttps://plantarum.izbis.bg.ac.rs/handle/123456789/378
dc.description.abstractAimsThe aim of this study was to address the toxicity of recently described polyene macrolide 32, 33-didehydroroflamycoin (DDHR) on a wide range of fungal pathogens and its potential to control plant fungal diseases. Methods and ResultsThe antifungal activity of DDHR invitro was examined against common human and plant pathogenic fungi using a broth microdilution assay and a disk diffusion assay. Minimum inhibitory concentrations ranged from 125 to 35gml(-1). A radial growth inhibition assay showed that DDHR inhibited mycelia growth, inducing mycelial necrosis and affecting sporulation. During the invivo assay on apple fruits administration of DDHR 1h before fungal inoculation inhibited spreading of the infection. Importantly, DDHR exhibited no phytotoxic effects on the model plant, Capsicum annum, verified by the plant growth rate and chlorophyll content. ConclusionsDDHR inhibits growth of various plant pathogens invitro with the strongest activity against Alternaria alternata, Colletotrichum acutatum and Penicillium expansum, and protects apple fruits from decay. Significance and Impact of the StudyThis is the first report of the inhibitory effect of DDHR on important pathogenic fungal isolates. DDHR could be a good scaffold for developing new antifungal agents for fruit and vegetable protection.en
dc.publisherWiley, Hoboken
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173048/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173005/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31018/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Applied Microbiology
dc.subject32-33-didehydroroflamycoinen
dc.subjectfungien
dc.subjecthuman pathogensen
dc.subjectplant pathogensen
dc.subjectpolyene macrolideen
dc.titleControl of human and plant fungal pathogens using pentaene macrolide 32, 33-didehydroroflamycoinen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage1434
dc.citation.issue6
dc.citation.other118(6): 1426-1434
dc.citation.rankM22
dc.citation.spage1426
dc.citation.volume118
dc.type.versionpublishedVersion
dc.identifier.doi10.1111/jam.12811
dc.identifier.pmid25810243
dc.identifier.scopus2-s2.0-84929509136
dc.identifier.wos000354570600017


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу